Establishment of a specialist hospital for chest diseases
Founded on November 2, 1957, the hospital established care, teaching and research in heart, lung, esophageal, tracheal and mediastinal diseases as its specialty foundation.
ShanghaiChest Hospital
Second nationally for thoracic surgery reputation, with lung cancer research in leading international medical journals.
Founded in 1957, Shanghai Chest Hospital has a specialist tradition in heart, lung, esophageal and tracheal diseases. Thoracic surgery ranked second nationally in the 2023 Fudan China Hospital Specialty Reputation Rankings and is a national key clinical specialty. In 2024, the Neotorch study led by Lu Shun and the LAURA study, on which he was first author, appeared in JAMA and NEJM respectively. Esophageal cancer research and complex airway reconstruction also have documented original contributions and international exchanges.
Shanghai, China
A heritage in chest specialties, with clinical research that advances treatment evidence
The hospital's strengths span two complementary areas: thoracic surgery addresses difficult esophageal, lung and airway conditions, while the lung tumor team conducts multicenter trials on treatment around surgery and in locally advanced disease. National specialty reputation and specific achievements attributable to teams and publications support its academic standing.
The national key clinical specialty in thoracic surgery and Shanghai Clinical Center for Lung Tumors connect surgical techniques, cancer treatment and multidisciplinary research.
National specialty standing and clinical research platforms
Rankings follow Fudan University's Hospital Management Institute 2023 China Hospital Specialty Reputation Rankings, published in November 2024.
Thoracic surgeryNo. 2 nationally
2023 Fudan China Hospital Specialty Reputation Rankings
Thoracic surgeryNational key clinical specialty
A national specialty listed in Shanghai Jiao Tong University School of Medicine's affiliated hospital introduction
Lung tumorsShanghai clinical medical center
Shanghai Jiao Tong University School of Medicine oncology team introduction
Specialty reputation rankings assess hospital disciplines, while clinical studies involve defined populations. Neither establishes an individual patient's treatment outcome.
Nationally prominent thoracic surgery addressing complex chest conditions
Thoracic surgery ranked second nationally in the 2023 Fudan Specialty Reputation Rankings. Its national key clinical specialty platform covers lung, esophageal and tracheal disease, connecting with oncology, respiratory medicine, radiotherapy and anesthesia. Esophageal cancer treatment research and complex airway reconstruction demonstrate distinct areas of technical depth.
Two lung cancer clinical studies in JAMA and NEJM
In 2024, Lu Shun's Neotorch study appeared in JAMA, investigating perioperative treatment for resectable stage II–III non-small-cell lung cancer. LAURA, with Lu as first author, appeared in NEJM and addressed treatment after chemoradiotherapy for unresectable, EGFR-mutated stage III lung cancer. The studies concern different disease stages and clinical questions.
Connecting esophageal cancer clinical research with immune mechanisms
Li Zhigang's team explored neoadjuvant immunotherapy combined with chemotherapy in the NICE study and published research into treatment response mechanisms in Cancer Cell in 2023. It identified a SPRY1-positive CD8 T-cell population associated with response, extending surgical patients' clinical questions into tumor immunology.
International surgical demonstration of complex minimally invasive airway techniques
Yao Feng was invited to Inselspital, Bern University Hospital in Switzerland, to demonstrate the country's first three-dimensional uniportal thoracoscopic bronchial reconstruction, sharing experience in complex minimally invasive airway repair.
Esophageal cancer immunotherapy mechanism research in Cancer Cell
Research with Li Zhigang as first-listed corresponding author linked clinical treatment response to a specific T-cell population, providing mechanistic evidence for studies of perioperative esophageal cancer treatment.
Lung cancer studies in two leading international medical journals
Neotorch and LAURA appeared in JAMA and NEJM respectively, covering perioperative treatment of resectable lung cancer and post-chemoradiotherapy treatment of unresectable, EGFR-mutated stage III lung cancer.
Leading specialties,
built on medical achievements.
Explore Chest Hospital's contributions in each field, from specialty standing to notable achievements, and the conditions this expertise supports.
No. 2 nationally in thoracic surgery
2023 Fudan China Hospital Specialty Reputation Rankings; ranking of the hospital's overall thoracic surgery discipline.
The second-place position in the 2023 Fudan Specialty Reputation Rankings reflects thoracic surgery as a whole. Esophageal surgery is represented by NICE and immune mechanism research; tracheal surgery has documented international bronchial reconstruction demonstrations and repair of tracheal stenosis with fistula.
The NICE study and immune mechanism findings in Cancer Cell
2023 · Clinical and translational researchLi Zhigang's team combined clinical research on neoadjuvant esophageal cancer treatment with mechanistic studies, exploring the association between SPRY1-positive CD8 T cells and immunotherapy response.
Switzerland's first three-dimensional uniportal thoracoscopic bronchial reconstruction
2019 · International surgical demonstrationYao Feng was invited to demonstrate complex bronchial reconstruction at Inselspital in Bern. This documented technical exchange reflects experience in minimally invasive surgery for central airway lesions.
Reconstruction for tracheal stenosis with tracheoesophageal fistula
2023 · A complex reconstruction caseAn institutional report documented Yao Feng's team treating a relatively long segment of tracheal stenosis with a fistula, illustrating technical challenges requiring coordinated airway reconstruction and esophageal repair.
Thoracic surgery: a national key clinical specialty
The hospital connects thoracic surgery with respiratory medicine, oncology, radiotherapy and anesthesia. Esophageal tumors, airway tumors and benign stenosis can be directed to different specialist assessments according to their nature.
What conditions can this expertise help address?
Esophageal cancer assessment requires pathology, stage and previous treatment. Airway stenosis or tracheoesophageal fistula requires details of lesion length, location and prior management. The relevant technical expertise differs; complete imaging, endoscopy and surgical records help identify the appropriate team.
Shanghai Clinical Center for Lung Tumors
Shanghai Jiao Tong University School of Medicine's team introduction. The national ranking is for thoracic surgery and is not applied to oncology.
Oncology focuses on multidisciplinary lung cancer care and precision treatment. The 2024 Neotorch and LAURA studies addressed treatment associated with surgery and unresectable locally advanced lung cancer respectively, demonstrating experience in large clinical trials across different treatment stages.
Neotorch: perioperative research in resectable lung cancer
2024 · JAMALu Shun led a randomized, double-blind, multicenter phase III trial evaluating toripalimab with platinum-based chemotherapy for resectable stage II–III non-small-cell lung cancer.
LAURA: post-chemoradiotherapy research in EGFR-mutated stage III lung cancer
2024 · NEJMLu Shun was the paper's first author. The study compared osimertinib with placebo in patients with unresectable, EGFR-mutated stage III disease without progression during or after chemoradiotherapy. The study population had defined eligibility criteria.
Multidisciplinary lung cancer care and national research projects
The institutional team introduction documents a lung cancer multidisciplinary team, national key R&D work and international multicenter clinical research experience, covering early diagnosis, targeted therapy, immunotherapy and combined treatment.
What conditions can this expertise help address?
Systemic lung cancer treatment depends on pathological type, stage, molecular testing and prior treatment response. The two representative studies concern different populations; actual care must be determined by the hospital using individual records.
Meet the specialists
through their achievements.
Discover the specialists' contributions and the conditions and treatments they focus on.
Showing 3 representative specialists
Li Zhigang
Thoracic surgery: esophagus and complex airways
Chief physician · Professor
Specialist in clinical and translational esophageal cancer research
Ask about this doctorWorking on the NICE study and serving as first-listed corresponding author of mechanistic research in Cancer Cell
Li Zhigang connects esophageal surgery with perioperative treatment research. In addition to totally minimally invasive esophageal cancer surgery, his institutional profile covers endoscopic treatment of early esophageal tumors and minimally invasive surgery for benign conditions such as gastroesophageal reflux and hiatal hernia.
Clinical research associated with the NICE esophageal cancer study
The team conducted NICE research on neoadjuvant immunotherapy combined with chemotherapy, studying treatment response and subsequent surgery and providing the clinical foundation for later translational research.
First-listed corresponding author of a 2023 Cancer Cell study
Starting from clinical samples, the research explored the association of SPRY1-positive CD8 T cells with esophageal cancer immunotherapy response, carrying questions from clinical trials into mechanistic investigation.
Conditions and treatment expertise
- Esophageal cancer and early esophageal tumors
- His institutional profile lists totally minimally invasive esophagectomy and endoscopic diagnosis and treatment of early esophageal cancer. His perioperative research focuses on connecting surgery with systemic treatment.
- Gastroesophageal reflux and hiatal hernia
- Minimally invasive surgical approaches to reflux disease and hiatal hernia, informed by existing endoscopy, imaging and functional tests.
Yao Feng
Thoracic surgery: esophagus and complex airways
Thoracic and tracheal surgeon
Complex airway reconstruction and international surgical demonstrations
Ask about this doctorDemonstrating three-dimensional uniportal bronchial reconstruction in Switzerland and repairing complex airway fistulas
Yao Feng's documented clinical work focuses on central airway lesions involving the trachea, carina and bronchi. Thoracoscopic bronchial reconstruction and repair of tracheal stenosis with tracheoesophageal fistula illustrate complex airway surgical expertise across different anatomical situations.
Invited to demonstrate Switzerland's first such procedure in 2019
He demonstrated three-dimensional uniportal thoracoscopic bronchial reconstruction at Inselspital, Bern University Hospital, bringing complex minimally invasive airway techniques into international exchange.
Complex repair of long-segment tracheal stenosis with fistula
A 2023 institutional report documented his team's reconstruction for a patient with tracheal stenosis and tracheoesophageal fistula, addressing complex repair between the respiratory and digestive passages.
Conditions and treatment expertise
- Tracheal, carinal and bronchial lesions
- His experience covers airway stenosis, central lung tumors and complex lesions requiring tracheal or bronchial reconstruction. The extent of surgery depends on lesion location and length.
- Tracheoesophageal fistula and complex airway repair
- Published cases illustrate reconstruction when tracheal stenosis and tracheoesophageal fistula coexist, requiring joint assessment of previous surgery, infection, fistula and airway conditions.
Lu Shun
Lung tumors: precision and combined treatment
Chief physician · Professor
Chief expert of a Ministry of Science and Technology key program
Ask about this doctorLeading Neotorch and publishing LAURA as first author
Lu Shun has long worked in early lung cancer diagnosis, precision treatment and combined care. His representative studies appeared in JAMA and NEJM, addressing perioperative treatment of resectable lung cancer and post-chemoradiotherapy treatment of unresectable, EGFR-mutated stage III disease.
Leading the phase III Neotorch study, published in JAMA
Published in 2024, the randomized, double-blind, multicenter study evaluated toripalimab plus platinum-based chemotherapy in resectable stage II–III non-small-cell lung cancer, with Lu Shun as leading investigator.
First author of the LAURA paper in NEJM
The 2024 LAURA study investigated osimertinib after chemoradiotherapy for unresectable, EGFR-mutated stage III non-small-cell lung cancer. Lu Shun is listed as first author.
Conditions and treatment expertise
- Targeted and precision treatment of lung cancer
- Research and clinical precision treatment based on tumor molecular characteristics, with representative studies addressing EGFR-mutated lung cancer and treatment after chemoradiotherapy.
- Immunotherapy and multidisciplinary combined treatment
- His expertise covers lung cancer immunotherapy and combined treatment. Perioperative research examines coordination of systemic treatment with surgery, assessed in light of pathology, stage and previous treatment.
These profiles describe professional expertise and notable experience. The doctor, campus and appointment time are confirmed when arranging care.
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