Poor control despite two medicines during pollen season: who can be assessed for stapokibart
In China, stapokibart (Kangyueda) can be used in adults with moderate-to-severe seasonal allergic rhinitis whose symptoms remain poorly controlled after treatment with an intranasal corticosteroid combined with an antihistamine. Before traveling, give the allergy specialist your medicine packaging and a calendar of symptom episodes; these provide more information than a positive allergen test alone.
Key points
- Write down the months and locations where your symptoms are worst and the medicines you have used.
- Compare costs separately for the actual amount used for the first dose and for each subsequent dose.
Give your doctor a clear picture of one pollen season
List, week by week, how nasal congestion, sneezing, a runny nose, and itchy eyes affect your sleep and daytime activities. Note whether symptoms occur at home, at work, or while traveling, and whether they ease after the season ends. List the generic names of your nasal sprays and antihistamines, how you use them, whether you use them together, and how long you have used them; demonstrate your nasal spray technique to your doctor to help identify any problems with its use.
Why distinguish rhinitis, nasal polyps, and asthma?
Your doctor needs to consider the season, your exposure history, a physical examination, and any necessary allergy tests to determine the cause of your symptoms. Be sure to mention year-round nasal congestion, a persistent reduction in your sense of smell, or recurrent wheezing. China first approved this medicine for atopic dermatitis in 2024, and the additional indication for moderate-to-severe seasonal allergic rhinitis in adults was announced in February 2025. A randomized phase III trial enrolled 108 adults, all with moderate-to-severe seasonal allergic rhinitis and a baseline blood eosinophil count of at least 300 cells per microliter. On a nasal symptom scale ranging from 0–12 points, the treatment group had an average improvement over the first two weeks that was 1.3 points greater than the placebo group. These findings describe the study population and the average effect; how much an individual improves still depends on symptoms and pollen exposure.
Can the treatment course fit into one trip?
The prescribing information for adult rhinitis specifies an initial dose of two 300 mg syringes, followed by one syringe every two weeks. Agree with your doctor on when to start, reassess, and end treatment based on the pollen season where you live and your symptoms, and clarify how to continue your existing nasal sprays. If you would like to continue injections locally, first have a local doctor check the prescription, product availability, and storage conditions.
Ask the pharmacy to quote the cost of several doses
Stapokibart 300 mg/2 mL: the reference medicine cost in China is CNY 1,039 per vial. Under the adult rhinitis regimen in the prescribing information, the medicine cost for the initial two-vial dose is CNY 2,078, followed by CNY 1,039 for each one-vial dose. Outpatient visits, injections, and any necessary allergy tests cost extra.
Frequently asked questions
Can children with pollen allergies use this medicine under this indication?
The indication verified here is seasonal allergic rhinitis in adults. Children should first be assessed by a pediatric allergy specialist based on their age.
If I have only used one oral antihistamine, can I book an injection straight away?
First have your doctor review whether you have used an intranasal corticosteroid together with an antihistamine, how you used them, and how well they worked.
If my rhinitis improves after I leave the place where I usually live, how can I judge the medicine’s effect?
Record your travel dates, local pollen conditions, and any medicines used at the same time. Reduced exposure itself can also change your symptoms.
Should I stop my existing nasal sprays before departure?
Ask the prescribing team to write down how each medicine should be continued or adjusted, so that you do not interrupt treatment on your own because of travel.
What if my next injection is due on the day I return to my home country?
Give your doctor your itinerary for both locations before the first dose, and have the care teams in both locations confirm where and when the next injection will be given; do not shorten the interval between doses on your own.